TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE

TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE - Names and Identifiers

Name	4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms	1-BOC-4-(2-FORMYLPHENYL)PIPERAZINE 1-Boc-4-(2-formylphenyl)piperazine 2-(N-BOC-PIPERAZIN-1-YL)BENZALDEHYDE 4-(2-FORMYLPHENYL)PIPERAZINE, N1-BOC PROTECTED 1-TERT-BUTOXYCARBONYL-4-(2-FORMYLPHENYL)PIPERAZINE TERT-BUTYL 4-(2-FORMYLPHENYL)-1-PIPERAZINECARBOXYLATE TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-(2-FORMYL-PHENYL)-PIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	174855-57-3
InChI	InChI=1/C16H22N2O3/c1-16(2,3)21-15(20)18-10-8-17(9-11-18)14-7-5-4-6-13(14)12-19/h4-7,12H,8-11H2,1-3H3

TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE - Physico-chemical Properties

Molecular Formula	C16H22N2O3
Molar Mass	290.36
Density	1.154±0.06 g/cm3(Predicted)
Melting Point	86-90°C(lit.)
Boling Point	425.3±40.0 °C(Predicted)
Flash Point	211°C
Vapor Presure	1.93E-07mmHg at 25°C
Appearance	Solid
pKa	2.48±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.561
Physical and Chemical Properties	WGK Germany:3

TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R43 - May cause sensitization by skin contact
Safety Description	S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
Hazard Note	Irritant
Hazard Class	6.1

TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE - Introduction

4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is an organic compound with the chemical formula C19H23N3O3.

Nature:
4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is a solid with a white to yellowish appearance. It is stable and not easily soluble in water, but soluble in some organic solvents such as ethanol, dimethylformamide and acetonitrile. Its melting point is about 75-80 degrees Celsius.

Use:
4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is an important organic synthesis intermediate. It can be used to synthesize drugs, pesticides and other organic compounds. For example, it can be used to synthesize some anti-tumor drugs and anti-platelet aggregation drugs.

Method:
The preparation of 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER can be carried out by the following steps: First, 4-hydroxybenzaldehyde and BOC-protected piperazine are reacted to generate 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER.

Safety Information:
When handling 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, you need to pay attention to the following safety precautions: Wear appropriate protective equipment, including chemical protective glasses, protective gloves and protective clothing. Avoid inhaling its dust or vapor, and maintain good ventilation. If contact with skin or eyes, rinse immediately and seek medical help. In addition, the compound should be kept away from fire and oxidizing agents, and remain sealed and moisture-proof during storage.

Last Update：2024-04-09 21:01:54